Resistance Hypertension

Resistance hypertension is high blood pressure that does not respond well to aggressive medical treatment. It is defined as failure to achieve goal blood pressures in patients taking optimal or maximum tolerated doses of three or more antihypertensive drugs, is estimated to occur in about 25% of hypertensive patients on treatment. Several factors have been identified as contributors to resistant hypertension. Poor patient adherence, physician inertia, inadequate doses or inappropriate combinations of antihypertensive drugs, excess alcohol intake, and volume overload are some of the most common causes of resistance.

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